Doctor counseling male patient with abdominal pain in hospital examination room

Key Takeaways

  • Remicade (infliximab) is an IV infusion therapy that reduces inflammation in the GI tract and helps manage moderate to severe Crohn’s disease and ulcerative colitis.
  • This treatment works by targeting TNF-alpha, a protein responsible for driving inflammation in the intestines, helping patients achieve symptom control and long-term remission.
  • Many patients experience reduced abdominal pain, diarrhea, cramping, bleeding, and flare frequency with consistent Remicade therapy.
  • Remicade is commonly recommended when oral medications are not effective or when patients need a biologic therapy to prevent disease progression.
  • Smart Infusion Therapy Services provides expert-administered Remicade infusions with private rooms, attentive monitoring, and patient-focused GI infusion care at locations in Eau Claire, Wausau, Onalaska, and Madison. Schedule an appointment today.

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How Remicade Works for IBD Management

Remicade (infliximab) is an FDA-approved biologic infusion therapy used to treat adults and children (ages 6+) with moderately to severely active Crohn’s disease or ulcerative colitis. It belongs to a class of medications known as TNF-alpha inhibitors, which help control inflammation by blocking proteins that trigger the body’s immune response.

Targeting TNF-Alpha to Reduce Intestinal Inflammation

In conditions like Crohn’s and ulcerative colitis, the immune system mistakenly attacks healthy tissue in the gastrointestinal tract. TNF-alpha, an inflammatory protein, plays a major role in this process.

By blocking TNF-alpha, Remicade helps:

  • Reduce inflammation in the intestinal lining
  • Improve symptoms such as abdominal pain, diarrhea, and bleeding
  • Promote mucosal healing
  • Lower the risk of flare-ups
  • Support long-term remission

This mechanism is especially beneficial for patients whose IBD symptoms persist despite traditional medications such as steroids or immunomodulators.

Benefits of Remicade for Crohn’s Disease & Ulcerative Colitis

1. Reduced Daily Symptoms

Crohn’s disease and ulcerative colitis cause chronic and often unpredictable symptoms, including:

  • Abdominal pain
  • Diarrhea
  • Cramping
  • Bloody stools
  • Weight loss
  • Fatigue

Remicade infusions can significantly reduce these symptoms by calming inflammation at the source. Patients often begin noticing improvement within weeks of starting treatment.

2. Helps Achieve and Maintain Remission

Long-term remission is a primary goal of IBD management, and Remicade plays a critical role in maintaining stable disease activity.

Remicade is approved for:

  • Induction therapy (initial symptom improvement)
  • Maintenance therapy (ongoing disease control)

Biosimilars like Avsola, Inflectra, and Renflexis, also offered at Smart Infusion Therapy, provide similar benefits and are approved for both Crohn’s and ulcerative colitis.

3. Helps Prevent Long-Term Complications

Uncontrolled IBD increases the risk of complications such as:

  • Fistulas
  • Strictures
  • Severe bleeding
  • Malnutrition
  • Increased hospitalization

By decreasing intestinal inflammation, Remicade helps protect the GI tract from progressive damage.

4. Improves Quality of Life

With fewer flare-ups and more predictable symptom control, patients often experience:

  • Better energy levels
  • Improved appetite
  • Better sleep
  • Restoration of daily activities

This can be life-changing for individuals who have struggled with chronic, debilitating symptoms.

Why Remicade Is a Preferred Long-Term Option for IBD

Remicade has been used for decades and remains a trusted treatment for Crohn’s and ulcerative colitis. Multiple factors contribute to its value in long-term GI health:

Proven success rates for IBD remission

Clinical studies and long-term patient outcomes show Remicade helps many patients achieve and maintain remission. It is also one of the most effective therapies for Crohn’s complications, such as fistulas.

Effective when other medications fail

If a patient has not responded well to steroids or oral immunosuppressants, Remicade offers a more targeted approach.

Fast-acting relief

Compared to some medications that take months to become effective, Remicade often provides noticeable symptom improvement early in treatment.

Compatible with comprehensive GI treatment plans

A gastroenterologist may pair Remicade with lifestyle adjustments, nutritional care, or other medical therapies to create a holistic plan for disease control.

How Remicade Fits Into a Comprehensive GI Treatment Plan

Specialist-Directed Therapy

Smart Infusion Therapy requires a treatment order from a gastroenterologist or primary care doctor before starting Remicade. Their team helps coordinate this order if a patient does not yet have one.

Consistent Infusion Schedule

Remicade is administered on a structured timeline:

  • Weeks 0, 2, and 6 for loading doses
  • Every 6–8 weeks thereafter

This schedule helps maintain steady inflammation control and prevent flare-ups.

Personalized Monitoring

Nurses monitor vitals before, during, and after infusion, ensuring safety and comfort. Because IBD symptoms can evolve, Smart Infusion supports ongoing communication with your GI specialist to ensure your therapy remains effective.

Comparison: Crohn’s vs. Ulcerative Colitis – How Remicade Helps

ConditionHow Remicade HelpsIdeal Candidates
Crohn’s DiseaseReduces inflammation throughout the GI tract; helps maintain remission; improves abdominal pain and diarrheaModerately to severely active Crohn’s not controlled by medications; pediatric or adult patients aged 6+
Ulcerative ColitisDecreases inflammation in the colon; reduces bleeding, cramping, and urgencyModerate to severe UC; steroid-dependent disease; inadequate response to immunomodulators

Both conditions benefit significantly from Remicade when symptoms impact daily life or fail to improve with standard therapies.

What to Expect During Remicade Infusion Therapy

Smart Infusion Therapy Services provides a comfortable and supportive infusion environment designed specifically for patients with GI conditions.

Comfort-Focused Infusion Suites

Patients receive their treatment in relaxing infusion rooms that include:

  • Comfortable reclining chairs
  • WiFi, Hulu, and entertainment
  • Snacks and beverages
  • A 1:3 nurse-to-patient ratio for close monitoring
  • Optional private rooms for additional comfort during GI infusions

The Infusion Process

  • A nurse places an IV and administers Remicade slowly over approximately 2 hours.
  • Throughout therapy, nurses monitor vital signs and ensure patient comfort.
  • Most patients return every 6–8 weeks for maintenance infusions.

Strengthen Your GI Care With Expert Remicade Infusion Support

Remicade is a proven, trusted therapy for managing Crohn’s disease and ulcerative colitis, helping patients reduce inflammation, control symptoms, and achieve meaningful remission. Smart Infusion Therapy Services offers safe, patient-focused Remicade infusion care with comfortable suites, attentive monitoring, and seamless communication with your GI specialist.

To begin, schedule an appointment with Smart Infusion Therapy Services for Remicade infusion therapy.

Frequently Asked Questions

What is Remicade used for?

Remicade treats moderate to severe Crohn’s disease and ulcerative colitis in adults and children aged six and older. It reduces inflammation by blocking TNF-alpha.

How does infliximab (Remicade) help Crohn’s disease and ulcerative colitis?

It targets TNF-alpha, lowers inflammation, improves symptoms, and promotes mucosal healing, key factors in managing IBD.

How often do I receive Remicade infusions?

After initial loading doses at weeks 0, 2, and 6, infusions are typically given every 6–8 weeks.

Do I need a GI specialist’s order to get Remicade?

Yes. Smart Infusion Therapy can help coordinate the required treatment order with your provider.

Is Remicade infusion therapy safe?

Yes. Remicade is widely used and generally well-tolerated, and Smart Infusion nurses provide continuous monitoring during each infusion.