Woman sitting in armchair while waiting for IV infusion in hospital

Key Takeaways

  • Remicade infusion therapy is used to treat autoimmune inflammatory conditions such as Crohn’s disease, ulcerative colitis, rheumatoid arthritis, and psoriatic arthritis.
  • Candidates typically include patients with moderate to severe disease, those who have not responded well to oral medications, or individuals needing targeted immune-modulating care.
  • Remicade works by blocking inflammatory proteins to reduce symptoms like abdominal pain, diarrhea, joint pain, stiffness, and chronic inflammation.
  • A GI or rheumatology specialist plays an essential role in evaluating whether Remicade is appropriate and providing the necessary treatment order.
  • Smart Infusion Therapy Services offers safe, comfortable, expert-administered Remicade infusions across Eau Claire, Wausau, Madison, and Onalaska, with a simple way to schedule your appointment.

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Understanding Remicade: What It Is and What It Treats

Remicade (infliximab) is an IV biologic infusion therapy used to treat several autoimmune inflammatory conditions. It is part of a class of medications known as TNF-alpha inhibitors, which work by blocking a protein in the immune system that triggers inflammation.

Smart Infusion Therapy provides Remicade infusion services for several conditions, including:

Crohn’s Disease

Remicade is FDA-approved for adults and children ages six and older with moderately to severely active Crohn’s disease. For individuals whose symptoms include abdominal pain, diarrhea, weight loss, or chronic inflammation, Remicade can help induce and maintain remission.

ULCERATIVE COLITIS

Patients with moderate to severe ulcerative colitis may also benefit from Remicade therapy, especially if they have not responded to other treatments. Remicade helps reduce inflammation in the colon and improve symptoms such as bloody stools, cramping, and fatigue.

RHEUMATOID ARTHRITIS

Smart Infusion provides Remicade infusions for adults with moderate to severe rheumatoid arthritis. The treatment can help reduce joint pain, swelling, stiffness, and overall disease progression when used alongside a specialist’s treatment plan.

Psoriatic Arthritis & Ankylosing Spondylitis

Remicade also benefits individuals with psoriatic arthritis or ankylosing spondylitis by reducing inflammation, improving mobility, and helping prevent long-term joint damage.

How Remicade Works to Reduce Inflammation

Targeting TNF-Alpha for Autoimmune Control

Remicade works by targeting TNF-alpha, a protein responsible for stimulating inflammation in the body. People with autoimmune diseases often produce too much TNF-alpha, causing damage to the gastrointestinal tract or joints.

By blocking TNF-alpha, Remicade can:

  • Decrease inflammation
  • Reduce symptoms like pain, diarrhea, and swelling
  • Promote mucosal healing in Crohn’s and ulcerative colitis
  • Slow or prevent joint damage in rheumatoid or psoriatic arthritis

This targeted mechanism allows Remicade to deliver relief when other therapies fall short.

Who Is a Good Candidate for Remicade Infusion Therapy?

Remicade is typically recommended for patients whose symptoms are moderate to severe and who need a stronger, more precise approach than oral medications alone.

1. Patients with Moderate to Severe IBD

Individuals experiencing persistent symptoms of Crohn’s disease or ulcerative colitis may benefit greatly from Remicade. It is particularly useful for patients who have:

  • Frequent flare-ups
  • Inadequate relief from steroids or immunomodulators
  • Symptoms that interfere with daily life
  • Signs of progressive disease

2. Individuals Who Have Not Responded to Traditional Medications

If oral medications or injections have not successfully controlled inflammation, Remicade may offer more effective immune modulation.

3. Patients Needing Biologic Therapy as First-Line Treatment

In some cases, especially with extensive disease or complications such as fistulas or severe joint involvement, a specialist may recommend Remicade earlier in the treatment plan.

4. Those with Autoimmune Joint Disease

Rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis often require a biologic therapy like Remicade when symptoms significantly affect daily function. Smart Infusion provides several infusion biologics for these conditions, including Remicade and FDA-approved biosimilars such as Avsola, Inflectra, and Renflexis.

What to Expect During Remicade Infusion Therapy

Smart Infusion Therapy Services prioritizes patient comfort and safety throughout every infusion appointment.

A Comfortable Infusion Experience

Patients receive treatment in relaxing infusion suites with comfortable seating, WiFi, entertainment options, and a supportive on-site care team. Smart Infusion offers private rooms for those who need additional privacy during GI-related infusions.

The Infusion Process

  • A nurse places an IV and administers the medication slowly over approximately 2 hours.
  • A 1:3 nurse-to-patient ratio ensures attentive monitoring.
  • Snacks, beverages, and support are provided throughout the appointment.

Who Can Provide the Treatment Order?

A specialist, such as a gastroenterologist or rheumatologist, must provide an order for Remicade infusion therapy. If you do not yet have an order, Smart Infusion can help coordinate with your existing care team to obtain one.

Signs It May Be Time to Consider Remicade

Many patients turn to Remicade when:

  • Symptoms persist despite current medications
  • Flare-ups become more frequent or severe
  • Inflammation appears on diagnostic tests
  • Joint pain or GI symptoms disrupt daily life
  • A specialist recommends a biologic therapy for long-term control.

If your current treatment plan is not providing adequate relief, Smart Infusion Therapy Services can help facilitate biologic infusion care prescribed by your specialist.

Common Questions About Remicade Infusion Side Effects

Remicade is widely used and generally well-tolerated, but like any biologic therapy, it may cause side effects.

Possible Infusion-Related Side Effects

  • Fatigue
  • Headache
  • Mild fever or chills
  • Temporary flushing
  • Injection site reactions

Specialists assess your health history and overall condition to ensure Remicade is appropriate. Throughout each infusion, Smart Infusion’s clinical team carefully monitors patients for safety and comfort.

Conditions Treated With Remicade: Quick Comparison Table

ConditionHow Remicade HelpsWho Typically Benefits
Crohn’s DiseaseReduces GI inflammation, maintains remissionModerately to severely active disease not controlled by oral meds
Ulcerative ColitisImproves symptoms and promotes mucosal healingPatients with persistent flares or steroid-dependent UC
Rheumatoid ArthritisReduces joint pain and slows disease progressionAdults with moderate–severe RA requiring biologic therapy
Psoriatic ArthritisDecreases inflammation and improves joint mobilityAdults whose symptoms interfere with daily activities
Ankylosing SpondylitisReduces spine and joint inflammationThose with chronic back pain and stiffness

When to Talk to a Specialist About Remicade

If your symptoms are worsening or your quality of life is declining, a gastroenterologist or rheumatologist can help determine whether Remicade may be appropriate. Once a provider writes the treatment order, Smart Infusion Therapy makes starting care simple with convenient scheduling and multiple Wisconsin locations.

Empower Your Treatment Plan With Biologic Infusion Expertise

Remicade is a trusted treatment for autoimmune GI disorders such as Crohn’s disease and ulcerative colitis. For many patients, it provides long-lasting symptom relief and improved quality of life when other medications are not enough. Smart Infusion Therapy Services delivers Remicade infusions in a comfortable, patient-focused environment with expert nursing care and seamless coordination with your GI specialist.

To get started, schedule an appointment with Smart Infusion Therapy Services for Remicade infusion therapy. Visit our Gastroenterology Services page or request an appointment online.

Frequently Asked Questions

What is Remicade used for?

Remicade is used to treat autoimmune inflammatory conditions, including Crohn’s disease, ulcerative colitis, rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. It works by blocking TNF-alpha, a protein that triggers inflammation.

How often do I receive Remicade infusions?

Most patients receive infusions every 6–8 weeks after completing the initial loading doses. Your specialist determines your dosing schedule.

Is Remicade safe?

Yes. Remicade is an FDA-approved biologic therapy widely used for autoimmune conditions. Smart Infusion Therapy’s trained medical team monitors patients throughout the infusion for safety and comfort.

Do I need a doctor’s order for Remicade?

Yes. A gastroenterologist or rheumatologist must provide an infusion order. Smart Infusion can help coordinate this if you don’t yet have one.

What are the common side effects of Remicade infusion?

Mild reactions may include fatigue, headache, dizziness, or temporary infusion-related discomfort. Most patients tolerate treatment well, and Smart Infusion’s nursing team monitors them closely during each appointment.