Every year, thousands of Americans receive a new diagnosis of multiple sclerosis (MS), a disease that impacts the brain, spinal cord, and immune system. While treatment options have expanded, one name stands out among the latest advancements: Briumvi. This novel therapy is transforming how people manage relapsing forms of MS by offering a faster, targeted, and more convenient treatment experience.
At Smart Infusion, we specialize in providing safe, accessible infusion treatments for neurological conditions like MS. With convenient centers in Eau Claire, Weston, Madison, and Onalaska, Wisconsin, our mission is to deliver expert care that supports stability and independence. If you're exploring advanced MS biologic therapies, our team is here to guide you every step of the way.
This article explores what makes Briumvi a standout choice for MS treatment, from its unique science to its benefits for patients.
What Sets Briumvi Apart From Other MS Treatments
Briumvi (ublituximab-xiiy) is a new medicine for MS approved by the FDA in 2022. It belongs to a class of MS biologic therapies that target immune system activity responsible for relapses and long-term damage.
Unlike many older medications, Briumvi explicitly targets CD20-positive B cells, a type of white blood cell that drives inflammation in MS. By removing these cells, Briumvi helps prevent attacks on the nervous system's protective covering (myelin), which is essential for proper nerve signaling.
What truly sets Briumvi apart is its balance of effectiveness and convenience, helping patients control disease activity while reducing time spent at the clinic.
The Science Behind Its Innovative Approach
Briumvi is classified as a monoclonal antibody therapy, designed through a process called glycoengineering. This means the antibody is modified at the molecular level to better recognize and eliminate harmful B cells.
Clinical trials known as ULTIMATE I and II showed that patients receiving Briumvi had:
- Lower annual relapse rates compared to standard therapies
- Reduced MRI activity, with fewer new lesions forming
- Slower progression of disability over two years
This evidence highlights why experts now consider Briumvi one of the best MS medications available for relapsing forms of the disease.
Patient Benefits: Convenience and Results
For patients, one of the most important advantages is treatment convenience. Briumvi is given by intravenous (IV) infusion in two initial doses, spaced two weeks apart. After that, it only requires an infusion once every six months.
The infusion process itself is also faster. Most Briumvi infusions take about one hour, compared to other therapies that may require up to three hours. This means less disruption to work, school, or family life.
Beyond convenience, patients on Briumvi may experience:
- Fewer relapses each year
- More stable MRI scans showing reduced disease activity
- Slowed progression of symptoms, helping preserve independence
This combination of outcomes makes Briumvi a strong choice for patients looking for both effectiveness and lifestyle flexibility.
Common Myths and Misconceptions About Briumvi
Some patients hesitate to start Briumvi because of outdated or incorrect information. Let’s clarify some common misconceptions:
“Is Briumvi a cure for MS?”
No current treatment cures MS. Briumvi helps manage disease activity, but it cannot reverse existing damage.
“Does Briumvi replace the need for other care?”
Briumvi is part of a long-term treatment plan, not a standalone solution. Healthy living, physical therapy, and regular monitoring remain essential.
“Are the side effects worse than other MS drugs?”
Like all biologics, Briumvi can cause infusion reactions such as fever, headache, or rash. However, studies suggest its infusion times are shorter and reactions may be less severe than some alternatives.
“Is Briumvi safe during pregnancy?”
Briumvi is not recommended for use during pregnancy or breastfeeding. Women are advised to avoid conceiving for six months after treatment.
Understanding how Briumvi fits into the landscape of MS biologic therapies empowers patients to make better treatment choices.
Why Briumvi Is Gaining Recognition in the MS Community
Briumvi is drawing attention for being a new medicine for MS that combines strong clinical results with a patient-centered treatment schedule. Neurologists value its ability to provide long-term disease control with fewer clinic visits.
It is also part of a growing group of MS biologic therapies designed to be more targeted, efficient, and tolerable. For many patients, this represents hope for new cures for MS symptoms, or more accurately, new ways to control the disease and preserve function.
When comparing Briumvi vs. Ocrevus, the most noted differences include:
- Infusion duration: About 1 hour for Briumvi, 2.5–3.5 hours for Ocrevus
- Antibody design: Briumvi’s glycoengineered structure may improve efficiency in depleting B cells
- Patient tolerability: Both have risks, but infusion reactions appear milder for Briumvi in some cases
These differences highlight why patients and providers alike are viewing Briumvi as an important advancement in MS care.
Let’s Take the Next Step Together
Not all MS treatments are alike, and Briumvi is proving to be a unique choice for MS management. With its targeted science, efficient infusion process, and meaningful results, it offers patients a way to stay more active and independent while reducing relapses. At Smart Infusion Therapy Services LLC, we are committed to helping patients access advanced therapies like Briumvi in a safe and supportive setting.
To learn more or to schedule your Briumvi infusion, contact us at (608) 690-7210 or complete our secure Appointment Request Form. proudly serve patients across Wisconsin with four accessible locations dedicated to exceptional MS care.
Frequently Asked Questions
How often do I need Briumvi infusions?
After two starter doses, Briumvi is infused once every six months.
What are the most common side effects?
Mild infusion reactions such as fever, fatigue, or rash are the most common.
Can I switch to Briumvi from another MS medication?
Yes, but your doctor will carefully plan timing to ensure safety.
Will my insurance cover Briumvi?
Many plans cover it, but prior authorization is usually required. Smart Infusion can assist with approvals.
Do I need vaccines before starting Briumvi?
Yes. Live vaccines should be avoided during treatment, so your doctor may recommend scheduling vaccines beforehand.
