Ocrevus (ocrelizumab) is quickly becoming one of the most trusted MS treatment options for patients seeking long-term relief and stability. Designed to address both relapsing and progressive forms of multiple sclerosis, this FDA-approved therapy is changing how MS is managed across the country.
At Smart Infusion, we specialize in delivering Ocrevus infusions in a calm, patient-centered setting across Wisconsin, including Eau Claire, Wausau, Madison, and Onalaska. Our experienced neurology infusion team partners closely with referring providers to ensure each patient receives safe, evidence-based care with personalized support at every step. Schedule your infusion or call 608-690-7210 to get started today.
Keep reading to explore why more people are making the switch—and how we can help guide your transition with confidence.
What Is Ocrevus Used For?
Ocrevus is a humanized monoclonal antibody designed to treat:
- Relapsing forms of MS: including relapsing-remitting MS (RRMS), active secondary progressive MS (SPMS), and clinically isolated syndrome (CIS)
- Primary progressive MS (PPMS): a steadily worsening form of MS without early relapses
The drug targets CD20-positive B cells, a type of immune cell involved in the inflammation and nerve damage associated with MS. By reducing these B cells, Ocrevus helps slow disease progression and reduce relapses.
How Ocrevus Works: Targeted Mechanism of Action
Ocrevus is not a broad immunosuppressant—it works with precision. Its active ingredient, ocrelizumab, is a monoclonal antibody that binds specifically to CD20 proteins found on certain B cells. These B cells are believed to play a central role in the inflammation and nerve damage associated with multiple sclerosis.
By targeting and depleting these CD20-positive B cells, Ocrevus helps reduce the immune system’s attack on the central nervous system. At the same time, it preserves other essential immune functions, which support a favorable safety profile.
This focused mechanism of action is what allows Ocrevus to slow disease progression in both relapsing and primary progressive MS, providing long-term protection without the widespread immune suppression seen in older MS treatments.
Benefits of Ocrevus Over Traditional MS Medications
Many patients are switching to Ocrevus after experiencing frequent relapses or side effects from older medications. Here's why this newer therapy stands out:
1. Proven Clinical Benefits
Clinical studies show that Ocrevus reduces the number of relapses and slows the progression of physical disability in patients with MS. These results often outperform earlier-generation treatments.
2. Longer Dosing Intervals
Unlike daily pills or weekly injections, Ocrevus infusion is given only twice a year after the first two loading doses. This low-maintenance schedule helps patients stay on track without disrupting work or travel plans.
3. Reduced Immune Suppression
Unlike broad immunosuppressants, Ocrevus targets a specific group of B cells while leaving other parts of the immune system intact, minimizing risks of widespread immune dysfunction.
4. Brain Volume Preservation
Research suggests that Ocrevus may help maintain brain volume over time, which can contribute to better long-term function and cognition.
What to Consider Before Starting Ocrevus Infusion Therapy
Starting Ocrevus is a meaningful step in managing multiple sclerosis, but it’s important to make sure it’s the right fit for you. Here are key considerations to discuss with your neurologist before beginning treatment:
- Eligibility: Ocrevus is approved by the FDA for adults with relapsing forms of MS (including RRMS and active SPMS) and primary progressive MS (PPMS).
- Infusion Schedule: Treatment begins with two initial doses, given two weeks apart. After that, infusions are scheduled every six months.
- Pre-medications: To help reduce the risk of infusion-related reactions, your care team may recommend medications such as antihistamines, acetaminophen, or corticosteroids before treatment.
- Ongoing Monitoring: Regular bloodwork and follow-ups are needed to monitor your immune response and make sure the therapy remains effective and safe.
Once your neurologist confirms you’re ready, our team at Smart Infusion Therapy will work closely with your care provider to schedule your infusion and guide you through every step of the process.
Why Smart Infusion Is the Preferred Provider for Ocrevus Infusions
At Smart Infusion, we don’t just administer medication—we deliver care designed around your comfort, safety, and schedule. Patients managing multiple sclerosis trust us for a more personalized alternative to hospital-based infusions.
Here’s why more patients choose Smart Infusion for their Ocrevus infusions:
- Neurology-trained infusion specialists who understand the complexities of MS
- Private treatment rooms equipped with Wi-Fi, Hulu, snacks, and comfortable seating
- 3:1 nurse-to-patient ratio for attentive, one-on-one care
- Lower out-of-pocket costs compared to traditional hospital settings
- Convenient locations in Eau Claire, Wausau, Madison, and Onalaska
Our goal is to make your Ocrevus infusion experience as seamless and stress-free as possible. With flexible scheduling and a calming environment, we help you stay on track with treatment, so you can focus on feeling your best.
Get Started with Ocrevus at Smart Infusion Therapy
Ocrevus offers hope and stability for patients living with MS, and where you receive it matters. At Smart Infusion, we deliver care that’s clinically excellent, highly personalized, and close to home.
Schedule your Ocrevus consultation today or call us at 608-690-7210 to speak with our team. We’re ready to help you feel confident about your next step in MS treatment.
